Synthesis, in silico and in vitro evaluation of novel thiazole

Synthesis, in silico and in vitro evaluation of novel thiazole and thiadiazole derivatives as multifunctional neurotherapeutic agents.

Computational design, identification of novel lead compounds possessing thiazole/thiadiazole scaffolds and evaluation of their in vitro enzyme inhibition activity on multiple targets, i.e, Monoamine Oxidase-A/B (MAO-A/B) and Acetylcholinesterase (AChE) enzymes.